MRL871

• Catalog Number: orb746386
• Category: Small Molecules
• Description: MRL-871 (MRL871) is a potent, selective inhibitor of RORγt via allosteric inverse agonism, inhibits coactivator binding with IC50 of 7 nM; significantly reduces the IL17a mRNA levels in EL4 murine lymphoblast cell line at 10 uM.
• CAS Number: [1392809-08-3]
• MW: 444.794
• SMILES: C(O)(=O)C1=CC=C(C2C3=C(N(C(=O)C4=C(C(F)(F)F)C=CC=C4Cl)N=2)C=CC=C3)C=C1
• Formula: C₂₂H₁₂ClF₃N₂O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.