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Catalog Number | orb146117 |
---|---|
Category | Small Molecules |
Description | Monastrol is a reversible, cell-permeable inhibitor of the motor protein Eg5 (kinesin family protein 11, Kif11), blocking basal ATPase activity in vitro (IC50 = 6.1 μM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 μM |
CAS Number | [329689-23-8] |
MW | 292.4 |
SMILES | S=C1NC(C2=CC(O)=CC=C2)C(C(OCC)=O)=C(C)N1 |
Formula | C14H16N2O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Qian, Junbin et al. An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint Mol Cell, 68, 715-730.e5 (2017)
99.19% | |
329689-23-8 | |
292.35 | |
C14H16N2O3S |