ML359

• Catalog Number: orb746469
• Category: Small Molecules
• Description: ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays > 100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.
• CAS Number: [1069858-99-6]
• MW: 350.3712239
• SMILES: O1C=CC=C1C(N(CC)C1C2=CC3C=CC(=CC=3N=C2N(C)N=1)OC)=O
• Formula: C₁₉H₁₈N₄O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.