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Catalog Number | orb1685333 |
---|---|
Category | Small Molecules |
Description | ML266 |
CAS Number | 1462267-08-8 |
Purity | 98.45% |
MW | 496.35 |
SMILES | O(CC(NC1=CC=C(Br)C=C1)=O)C2=C(C(NCC(N(C)C3=CC=CC=C3)=O)=O)C=CC=C2 |
Formula | C24H22BrN3O4 |
Biological Activity | ML266, a glucocerebrosidase (GCase) chaperone with an IC50 of 2.5 µM, facilitates the transport of the mutant protein to the lysosome, thereby restoring GCase activity without inhibiting the enzyme's function. This compound shows promise for Gaucher disease research. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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