ML-792

• Catalog Number: orb1308029
• Category: Small Molecules
• Description: ML-792
• CAS Number: 1644342-14-2
• Purity: 98.22%
• MW: 551.41
• SMILES: C(=O)(C=1C(N[C@@H]2C[C@H](COS(N)(=O)=O)[C@@H](O)C2)=NC=NC1)C3=NN(CC4=CC(Br)=CC=C4)C=C3
• Formula: C₂₁H₂₃BrN₆O₅S
• Biological Activity: ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and > 100 μM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM, respectively).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.