MK-8353

• Catalog Number: orb573380
• Category: Small Molecules
• Description: MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK inhibitor that inhibits activated ERK1 and ERK2 in vitro, with IC50 values of 23.0 nM and 8.8 nM, respectively (IMAP kinase assay), and nonactivated ERK2, with an IC50 of 0.5 nM (MEK
• CAS Number: [1184173-73-6]
• MW: 691.8449
• SMILES: S(C([H])([H])[H])[C@]1(C(N([H])C2C([H])=C([H])C3=C(C(C4=C([H])N=C(C([H])=C4[H])OC([H])(C([H])([H])[H])C([H])([H])[H])=NN3[H])C=2[H])=O)C([H])([H])N(C([H])([H])C(N2C([H])([H])C([H])=C(C3C([H])=C([H])C(C4N=C([H])N(C([H])([H])[H])N=4)=C([H])C=3[H])C([H])([H])C2([H])[H])=O)C([H])([H])C1([H])[H]
• Formula: C₃₇H₄₁N₉O₃S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.