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Catalog Number | orb611564 |
---|---|
Category | Small Molecules |
Description | MK-8033 is a potent, specific, dual c-Met/Ron kinases inhibitor with IC50 of 1/7 nM, also potently inhibits oncogenic c-Met activation loop mutants Y1230C, Y1230H and Y1235D with IC50 of 0.6-1.2 nM. |
CAS Number | [1283000-43-0] |
MW | 507.9918828 |
SMILES | O=S(=O)(NCC1C=CC=CN=1)CC1C=C2C(=O)C3C(C=CC2=CC=1)=NC=C(C1C=NN(C)C=1)C=3.Cl |
Formula | C25H22ClN5O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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