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Catalog Number | orb363967 |
---|---|
Category | Small Molecules |
Description | MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; > 330-fold selective against PARP3, V-PARP and Tank1. |
CAS Number | [1038915-73-9] |
MW | 492.5899 |
SMILES | O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)N.O=S(C5=CC=C(C)C=C5)(O)=O |
Formula | C26H28N4O4S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1038915-73-9 |
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