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Catalog Number | orb1744189 |
---|---|
Category | Small Molecules |
Description | Miclxin |
CAS Number | 2494198-61-5 |
Purity | 99.57% |
MW | 441.52 |
SMILES | N(CC1=CC(OC)=CC=C1)C=2C3=C(N=C(N2)N4CC(CC4)C=5C=CC=NC5)C=C(OC)C=C3 |
Formula | C26H27N5O2 |
Biological Activity | Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent inhibitor of mutant β-catenin, which is involved in the Wnt signaling pathway.Miclxin induces β-catenin-dependent apoptosis, leading to mitochondrial damage and loss of mitochondrial membrane. Miclxin has anti-tumor activity and kills tumors by targeting MIC60. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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