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Catalog Number | orb1297974 |
---|---|
Category | Small Molecules |
Description | MF-766 |
CAS Number | 1050656-06-8 |
Purity | 98% |
MW | 478.46 |
SMILES | OC(c1ccc(C2(CC2)NC(c2c3n(Cc4ccc(C(F)(F)F)cc4)ccc3ccc2)=O)cc1)=O |
Formula | C27H21F3N2O3 |
Biological Activity | MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. It can be used for cancer and inflammation diseases research[1][2]. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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