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Melanotan II acetate

Melanotan II acetate

Catalog Number: orb1737921

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Catalog Numberorb1737921
CategorySmall Molecules
DescriptionMelanotan II acetate
CAS Number1036322-26-5
Purity0.98
MW1084.23
SMILESC(C)(O)=O.C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC3=O
FormulaC52H73N15O11
Biological ActivityMelanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases in sensory nerve conduction velocity. Melanotan II acetate increases oxygen consumption and protein levels of uncoupling protein 1 (UCP1) in brown adipose tissue homogenates and decreases food intake, body weight, and serum levels of leptin, glucose, insulin, and cholesterol.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.