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Catalog Number | orb1737921 |
---|---|
Category | Small Molecules |
Description | Melanotan II acetate |
CAS Number | 1036322-26-5 |
Purity | 0.98 |
MW | 1084.23 |
SMILES | C(C)(O)=O.C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC3=O |
Formula | C52H73N15O11 |
Biological Activity | Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases in sensory nerve conduction velocity. Melanotan II acetate increases oxygen consumption and protein levels of uncoupling protein 1 (UCP1) in brown adipose tissue homogenates and decreases food intake, body weight, and serum levels of leptin, glucose, insulin, and cholesterol. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |