Medetomidine

• Catalog Number: orb1909168
• Category: Small Molecules
• Description: Medetomidine
• CAS Number: 86347-14-0
• MW: 200.28
• SMILES: C(C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2
• Formula: C₁₃H₁₆N₂
• Biological Activity: Medetomidine (Domtor) is a potent, highly selective α2-adrenoceptor agonist, demonstrating Ki values of 1.08 nM for α2-adrenoceptors and 1750 nM for α1-adrenoceptors, indicating significant selectivity for α2 over α1 receptors compared to clonidine and UK 14,304 with 1620-, 220-, and 300-fold respectively. Medetomidine significantly inhibits the twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0), showcasing its efficacy. Exhibiting a wide range of pharmacological effects, Medetomidine is effective in vivo, manifesting hypotensive, bradycardic, sedative, anxiolytic, hypothermic, and analgesic properties.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.