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Catalog Number | orb2279085 |
---|---|
Category | Small Molecules |
Description | MC-Val-Cit-PAB-Exatecan |
CAS Number | 2504068-28-2 |
MW | 1034.1 |
SMILES | N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN2C(=O)C=CC2=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8 |
Formula | C53H60FN9O12 |
Biological Activity | MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a conjugate of the DNA topoisomerase I inhibitor DX-8951 and a cathepsin-cleavable antibody-drug conjugate (ADC) linker, designed for targeted cancer therapy applications. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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