MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

• Catalog Number: orb1982682
• Category: Small Molecules
• Description: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
• CAS Number: 2414254-51-4
• MW: 1074.12
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)[C@H](OCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)C6CC6)c(c3Cn1c2=O)c45
• Formula: C₅₅H₆₀FN₉O₁₃
• Biological Activity: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is an agent-linker conjugate for antibody-drug conjugates (ADCs), incorporating Exatecan, a DNA Topoisomerase I inhibitor (IC 50 = 2.2 μM) [1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.