Marizomib

• Catalog Number: orb1707013
• Category: Small Molecules
• Description: Marizomib
• CAS Number: 437742-34-2
• Purity: 99.13%
• MW: 313.78
• SMILES: [C@@H](O)([C@]12[C@](C)([C@@H](CCCl)C(=O)N1)OC2=O)[C@]3(CCCC=C3)[H]
• Formula: C₁₅H₂₀ClNO₄
• Biological Activity: Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectively.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.