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Catalog Number | orb1301149 |
---|---|
Category | Small Molecules |
Description | Maraviroc |
CAS Number | 376348-65-1 |
Purity | 100.00% |
MW | 513.67 |
SMILES | C(C[C@H](NC(=O)C1CCC(F)(F)CC1)C2=CC=CC=C2)N3[C@@]4(C[C@@H](C[C@]3(CC4)[H])N5C(C(C)C)=NN=C5C)[H] |
Formula | C29H41F2N5O |
Biological Activity | Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98%(HPLC) | |
376348-65-1 |
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