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Catalog Number | orb1688215 |
---|---|
Category | Small Molecules |
Description | M1002 |
CAS Number | 823830-85-9 |
Purity | 98% |
MW | 394.29 |
SMILES | FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F |
Formula | C15H8F6N2O2S |
Biological Activity | M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation.M1002 alters the Tyr2 conformation of the HIF-281alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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