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Catalog Number | orb1731719 |
---|---|
Category | Antibodies |
Description | Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | Recombinant protein of mouse MCSF Receptor |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 109 kDa; Observed MW: 109 kDa |
Entrez | 12978 |
UniProt ID | P09581 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-on Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IH, WB | |
Human, Mouse, Rat, Zebrafish | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, IF, IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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