M-110

• Catalog Number: orb1707025
• Category: Small Molecules
• Description: M-110
• CAS Number: 1395048-49-3
• Purity: 98.30%
• MW: 445.94
• SMILES: C(=NNC(=O)C=1C=C(NCCCN2CCOCC2)N=CC1)(CC)C3=C(O)C=C(Cl)C=C3
• Formula: C₂₂H₂₈ClN₅O₃
• Biological Activity: M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.