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Catalog Number | orb1306433 |
---|---|
Category | Small Molecules |
Description | LY2109761 |
CAS Number | 700874-71-1 |
Purity | 99.64% |
MW | 441.52 |
SMILES | O(CCN1CCOCC1)C2=CC3=C(C(C=4C(=NN5C4CCC5)C6=CC=CC=N6)=CC=N3)C=C2 |
Formula | C26H27N5O2 |
Biological Activity | LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
700874-71-1 |
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