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Catalog Number | orb1301106 |
---|---|
Category | Small Molecules |
Description | LY-411575 |
CAS Number | 209984-57-6 |
Purity | 99.38% |
MW | 479.48 |
SMILES | C[C@H](NC(=O)[C@@H](O)c1cc(F)cc(F)c1)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O |
Formula | C26H23F2N3O4 |
Biological Activity | LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |