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Catalog Number | orb1308092 |
---|---|
Category | Small Molecules |
Description | LY 345899 |
CAS Number | 10538-99-5 |
Purity | 99.69% |
MW | 471.42 |
SMILES | O=C1N2C3=C(NCC2(CN1C4=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C4)[H])NC(N)=NC3=O |
Formula | C20H21N7O7 |
Biological Activity | LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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