LOXO-292(Selpercatinib)

• Catalog Number: orb573122
• Category: Small Molecules
• Description: Selpercatinib is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively. Antineoplastic activity.
• CAS Number: [2152628-33-4]
• MW: 525.6
• SMILES: N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
• Formula: C₂₉H₃₁N₇O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.