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LLY-283

LLY-283

Catalog Number: orb1707062

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Catalog Numberorb1707062
CategorySmall Molecules
DescriptionLLY-283
CAS Number2040291-27-6
Purity98.91%
MW342.35
SMILES[H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1
FormulaC17H18N4O4
Biological ActivityLLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • LLY-283 [orb691941]

    [2040291-27-6]

    342.36

    C17H18N4O4

    1 g, 100 mg, 250 mg