LLY-283

• Catalog Number: orb1707062
• Category: Small Molecules
• Description: LLY-283
• CAS Number: 2040291-27-6
• Purity: 98.91%
• MW: 342.35
• SMILES: O[C@H]1[C@H](N2C=3C(C=C2)=C(N)N=CN3)O[C@]([C@H](O)C4=CC=CC=C4)([C@H]1O)[H]
• Formula: C₁₇H₁₈N₄O₄
• Biological Activity: LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.