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Catalog Number | orb1707062 |
---|---|
Category | Small Molecules |
Description | LLY-283 |
CAS Number | 2040291-27-6 |
Purity | 98.91% |
MW | 342.35 |
SMILES | [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1 |
Formula | C17H18N4O4 |
Biological Activity | LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |