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Catalog Number | orb2664307 |
---|---|
Category | Small Molecules |
Description | LL-K12-18 is a bispecific molecular glue that enhances the protein-protein interaction between the CDK12-DDB1 complex, stabilizing the complex and thereby promoting the degradation of cyclin K (IC50=0.37 nM). This compound exhibits potent transcriptional repression and antiproliferative effects in tumor cells. LL-K12-18 is suitable for cancer research applications. |
Purity | 98.00% |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |