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Lifirafenib
Catalog Number: orb573381
| Catalog Number | orb573381 |
|---|---|
| Category | Small Molecules |
| Description | Lifirafenib (BGB-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant. |
| CAS Number | [1446090-79-4] |
| MW | 478.42 |
| SMILES | C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)O[C@H]5[C@@H]4[C@@H]5C6=NC7=C(N6)C=C(C=C7)C(F)(F)F |
| Formula | C25H17F3N4O3 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Lifirafenib [orb1905876]
98.25%
1446090-79-4
478.42
C25H17F3N4O3
50 mg, 100 mg, 1 mL*10mM (in DMSO), 25 mg, 10 mg, 1 mg, 5 mg
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