Lifirafenib

• Catalog Number: orb1905876
• Category: Small Molecules
• Description: Lifirafenib
• CAS Number: 1446090-79-4
• Purity: 98.25%
• MW: 478.42
• SMILES: O(C=1C=C2[C@]3([C@@H]([C@]3(OC2=CC1)[H])C=4NC=5C(N4)=CC=C(C(F)(F)F)C5)[H])C6=C7C(NC=C6)=NC(=O)CC7
• Formula: C₂₅H₁₇F₃N₄O₃
• Biological Activity: Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.