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Catalog Number | orb2565874 |
---|---|
Category | Small Molecules |
Description | Lifirafenib (BGB-283) maleate, a novel inhibitor targeting both Raf Kinase and EGFR, exhibits potent activity with IC50 values of 23 nM and 29 nM against recombinant BRaf V600E and EGFR, respectively [1]. |
CAS Number | 1854985-74-2 |
Purity | 98.00% |
MW | 1305.06 |
SMILES | OC(/C=C\C(O)=O)=O.[H][C@@]12[C@@H](C(NC3=C4)=NC3=CC=C4C(F)(F)F)[C@]1([H])C5=CC(OC6=C7C(NC=C6)=NC(CC7)=O)=CC=C5O2.OC(/C=C\C(O)=O)=O.[H][C@@]89[C@@H](C(NC%10=C%11)=NC%10=CC=C%11C(F)(F)F)[C@]8([H])C%12=CC(OC%13=C%14C(NC=C%13)=NC(CC%14)=O)=CC=C%12O9.OC(/C=C\C(O)=O)=O |
Formula | C62H46F6N8O18 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |