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Catalog Number | orb1310532 |
---|---|
Category | Small Molecules |
Description | Lenvatinib |
CAS Number | 417716-92-8 |
Purity | 99.80% |
MW | 426.85 |
SMILES | O(C=1C2=C(C=C(OC)C(C(N)=O)=C2)N=CC1)C3=CC(Cl)=C(NC(NC4CC4)=O)C=C3 |
Formula | C21H19ClN4O4 |
Biological Activity | Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM). Lenvatinib has strong anti-tumor activity. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
417717-04-5 | |
412.83 | |
C20H17ClN4O4 |
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