LEM-14-1189

• Catalog Number: orb1744526
• Category: Small Molecules
• Description: LEM-14-1189
• CAS Number: 2987501-17-5
• Purity: 97.98%
• MW: 682.81
• SMILES: C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)CN(CCCNC(=O)C4=CC5=CC=CC=C5C(=O)O4)CC6=NC7=C(C8=C(S7)CCCC8)C(=O)N6
• Formula: C₃₅H₃₄N₆O₅S₂
• Biological Activity: Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.