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Catalog Number | orb1309493 |
---|---|
Category | Small Molecules |
Description | LCH-7749944 |
CAS Number | 796888-12-5 |
Purity | 99.28% |
MW | 350.41 |
SMILES | N(CC1CCCO1)C=2C3=C(N=C(NC4=CC(OC)=CC=C4)N2)C=CC=C3 |
Formula | C20H22N4O2 |
Biological Activity | LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
796888-12-5 |
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