LC3-mHTT-IN-AN1 (Compound AN1)

• Catalog Number: orb746445
• Category: Small Molecules
• Description: LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
• CAS Number: [486443-73-6]
• MW: 411.04
• SMILES: BrC1C=C2/C(=C/C3C=C(O)C(O)=C(Br)C=3)/C(=O)NC2=CC=1
• Formula: C₁₅H₉Br₂NO₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.