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Catalog Number | orb757624 |
---|---|
Category | Small Molecules |
Description | Sacubitrilat, also known as LBQ-657, is endopeptidase inhibitor. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. |
CAS Number | [149709-44-4] |
MW | 383.444 |
SMILES | O=C(O)[C@H](C)C[C@H](NC(CCC(O)=O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1 |
Formula | C22H25NO5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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