LB244

• Catalog Number: orb2277728
• Category: Small Molecules
• Description: LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-dependent inflammatory diseases. However, pharmacokinetic studies have shown that LB244 exhibits limited oral activity in mice [1].
• Purity: 98.00%
• MW: 537.57
• SMILES: O=C(N[C@@H](CCCCNC(C1=CC=C([N+]([O-])=O)O1)=O)C2=NC(C=CC=C3)=C3N2)C(C=C4)=CC=C4C5=CC=CC=C5
• Formula: C₃₀H₂₇N₅O₅
• Biological Activity: LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-dependent inflammatory diseases. However, pharmacokinetic studies have shown that LB244 exhibits limited oral activity in mice [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.