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Catalog Number | orb1689983 |
---|---|
Category | Small Molecules |
Description | Lazertinib |
CAS Number | 1903008-80-9 |
Purity | 99.96% |
MW | 554.64 |
SMILES | C(N(C)C)C=1C(=NN(C1)C2=NC(NC3=C(OC)C=C(C(NC(C=C)=O)=C3)N4CCOCC4)=NC=C2)C5=CC=CC=C5 |
Formula | C30H34N8O3 |
Biological Activity | Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1903008-80-9 |
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