Lapatinib tosylate

• Catalog Number: orb1744815
• Category: Small Molecules
• Description: Lapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
• CAS Number: 1187538-35-7
• Purity: 98.00%
• MW: 753.26
• SMILES: O=S(=O)(O)C1=CC=C(C=C1)C.O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2
• Formula: C₃₆H₃₄ClFN₄O₇S₂
• Biological Activity: Lapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.