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Lapatinib tosylate

Lapatinib tosylate

Catalog Number: orb1744815

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Catalog Numberorb1744815
CategorySmall Molecules
DescriptionLapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
CAS Number1187538-35-7
Purity98.00%
MW753.26
SMILESO=S(=O)(O)C1=CC=C(C=C1)C.O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2
FormulaC36H34ClFN4O7S2
Biological ActivityLapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.