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Catalog Number | orb1310962 |
---|---|
Category | Small Molecules |
Description | Lapatinib |
CAS Number | 231277-92-2 |
Purity | 99.89% |
MW | 581.06 |
SMILES | N(C=1C2=C(C=CC(=C2)C=3OC(CNCCS(C)(=O)=O)=CC3)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4 |
Formula | C29H26ClFN4O4S |
Biological Activity | Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥99% | |
388082-78-8 | |
925.46 | |
C26H26ClFN4O4S 2C7H8O3S H2O |
> =98% | |
388082-77-7 | |
925.46 | |
C29H26ClFN4O4S.2C7H8O3S |