KY19382

• Catalog Number: orb1298435
• Category: Small Molecules
• Description: KY19382
• CAS Number: 2226664-93-1
• Purity: 98.06%
• MW: 360.19
• SMILES: O=C1C(C=2C(N1)=CC(Cl)=C(Cl)C2)=C3C(=NOC)C=4C(N3)=CC=CC4
• Formula: C₁₇H₁₁Cl₂N₃O₂
• Biological Activity: KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.