KY19382

• Catalog Number: orb1298435
• Category: Small Molecules
• Description: KY19382
• CAS Number: 2226664-93-1
• Purity: 98.06%
• MW: 360.19
• SMILES: CO\N=C1/C(/Nc2ccccc/12)=C1/C(=O)Nc2cc(Cl)c(Cl)cc12
• Formula: C₁₇H₁₁Cl₂N₃O₂
• Biological Activity: KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.