KY-05009

• Catalog Number: orb1309503
• Category: Small Molecules
• Description: KY-05009
• CAS Number: 1228280-29-2
• Purity: 98.06%
• MW: 352.41
• SMILES: N(C(=O)C1=CC=C(C)C=C1)C2=C(C(N)=O)N=C(NC3=CC=CC=C3)S2
• Formula: C₁₈H₁₆N₄O₂S
• Biological Activity: KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.