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Catalog Number | orb1300661 |
---|---|
Category | Small Molecules |
Description | KU-0060648 |
CAS Number | 881375-00-4 |
Purity | 99.21% |
MW | 582.71 |
SMILES | N(C(CN1CCN(CC)CC1)=O)C2=C3C(=C(C=C2)C4=C5C(C(=O)C=C(O5)N6CCOCC6)=CC=C4)SC=7C3=CC=CC7 |
Formula | C33H34N4O4S |
Biological Activity | KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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