KRAS inhibitor-9

• Catalog Number: orb1298658
• Category: Small Molecules
• Description: KRAS inhibitor-9
• CAS Number: 300809-71-6
• Purity: 99.94%
• MW: 292.81
• SMILES: NC1=CC(Cl)=C(SC2=NC3=C(S2)C=CC=C3)C=C1
• Formula: C₁₃H₉ClN₂S₂
• Biological Activity: KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.