KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody

• Catalog Number: orb1972660
• Category: Antibodies
• Description: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
• Clonality: Polyclonal
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• Note: For research use only
• Expiration Date: 12 months from date of receipt.