Kaempferol 5,7,4'-trimethyl ether

SKU: orb1682272

Description

This small molecule, kaempferol 5,7,4'-trimethyl ether, acts as an NF-κB inhibitor by targeting the p65 subunit. It demonstrates anti-proliferative activity in colon cancer cell lines like HT-29 and suppresses inflammatory NO production in macrophages, supporting its utility in oncology and inflammation research.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1098-92-6
• MW: 328.32
• Formula: C₁₈H₁₆O₆
• SMILES: O=C1C(O)=C(OC2=CC(OC)=CC(OC)=C12)C=3C=CC(OC)=CC3
• Target: NF-κB,NO Synthase
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (10.05 mM);DMSO:80 mg/mL (243.66 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3-Hydroxy-5,7,4′-trimethoxyflavone, Kaempferol 5,7,4' trimethyl ether, Kaempferol 5,7,4'trimethyl ether, Kaempferol 5,7,4'-trimethyl ether

Compound Identifiers

PubChem CID

624831