JNJ-7706621

• Catalog Number: orb181042
• Category: Small Molecules
• Description: JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing > 6-fold selectivity for CDK1/2 than CDK3/4/6; also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.
• CAS Number: [443797-96-4]
• MW: 394.356
• SMILES: S(C1C([H])=C([H])C(=C([H])C=1[H])N([H])C1N=C(N([H])[H])N(C(C2C(=C([H])C([H])=C([H])C=2F)F)=O)N=1)(N([H])[H])(=O)=O
• Formula: C₁₅H₁₂F₂N₆O₃S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.