JND3229

• Catalog Number: orb1707161
• Category: Small Molecules
• Description: JND3229
• CAS Number: 2260886-64-2
• Purity: 98%
• MW: 617.18
• SMILES: O=C1N(C=2C(CN1C3=C(Cl)C=CC=C3)=CN=C(NC4=CC(C)=C(C=C4)N5CCN(C)CC5)N2)[C@H]6CC[C@H](NC(CC)=O)CC6
• Formula: C₃₃H₄₁ClN₈O₂
• Biological Activity: JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.