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JI051

JI051

Catalog Number: orb1709367

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Catalog Numberorb1709367
CategorySmall Molecules
DescriptionJI051
CAS Number2234281-75-3
Purity≥98.0%
MW364.44
SMILESCCOc1ccccc1CCNC(=O)\C=C\c1c[nH]c2c(OC)cccc12
FormulaC22H24N2O3
Biological ActivityJI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inhibits the proliferation of HEK293 cells and pancreatic cancer cells.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • JI051 [orb611315]

    [2234281-75-3]

    364.4376

    C22H24N2O3

    1 g, 100 mg, 250 mg