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Catalog Number | orb1709367 |
---|---|
Category | Small Molecules |
Description | JI051 |
CAS Number | 2234281-75-3 |
Purity | ≥98.0% |
MW | 364.44 |
SMILES | CCOc1ccccc1CCNC(=O)\C=C\c1c[nH]c2c(OC)cccc12 |
Formula | C22H24N2O3 |
Biological Activity | JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inhibits the proliferation of HEK293 cells and pancreatic cancer cells. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |