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Catalog Number | orb692119 |
---|---|
Category | Small Molecules |
Description | JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. |
CAS Number | [2140807-05-0] |
MW | 543.61 |
SMILES | O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N(CC3=C4C=C(C5=CC=C(N6CCNCC6)C=C5)C=C3)C4=O |
Formula | C29H26FN5O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
2140807-05-0 |
95.85% | |
2140807-05-0 | |
543.61 | |
C29H26FN5O3S |
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