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Catalog Number | orb1709369 |
---|---|
Category | Small Molecules |
Description | JBJ-04-125-02 |
CAS Number | 2060610-53-7 |
Purity | 98% |
MW | 543.61 |
SMILES | [C@@H](C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C4=CC=C(C=C4)N5CCNCC5)C6=C(O)C=CC(F)=C6 |
Formula | C29H26FN5O3S |
Biological Activity | JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
2140807-05-0 |
95.85% | |
2140807-05-0 | |
543.61 | |
C29H26FN5O3S |
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