JAK3-IN-1

• Catalog Number: orb1707165
• Category: Small Molecules
• Description: JAK3-IN-1
• CAS Number: 1805787-93-2
• MW: 508.02
• SMILES: O(C)C=1C=C(C=CC1NC=2N=C(NCC3=CC(NC(C=C)=O)=CC=C3)C(Cl)=CN2)N4CCN(C)CC4
• Formula: C₂₆H₃₀ClN₇O₂
• Biological Activity: JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.