JAK Inhibitor I

• Catalog Number: orb181055
• Category: Small Molecules
• Description: Merck 5 is a potent and reversible ATP-competitive inhibitor of the JAK kinases (JAK1, JAK2, JAK3, and Tyk2). It also blocks IL2 and IL4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5.
• CAS Number: [457081-03-7]
• MW: 309.3
• SMILES: CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O
• Formula: C₁₈H₁₆FN₃O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.